Allergen Details:
| Allergen name: | Aca s 13 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Sarcoptiformes Species: Acarus siro (Storage mite) NCBI Taxomony ID: 66546 |
| Biochemical name: | Cytosolic fatty acid-binding protein |
| MW(SDS-PAGE): | 15 kDa |
| Allergenicity: | 3 out of 13 (23%) A. siro RAST-positive patients showed strong IgE binding to rAca s 13 on immunoblot |
| Allergenicity reference: | PubMed:10474032 |
| Route of allergen exposure: | Airway |
| Date Created: | 22-04-2003 |
| Last Updated: | 2023-11-09 14:06:40 |
| Submitter Info: | |
| Name: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Aca s 13.0101 | DQ979802.1 | ABL09307.1 | B0KZJ6 |
I looked at the IAAI paper by Eriksson, Whitley etc., 1999, PMID 10474032. The data indicates that it matches the description in the submission for the original entry. The sequence identified by them was 192 bp, and 64 aa. A cDNA clone of 396 bp, representing 131 aa with 64 of the first 66 aa identical to the Eriksson sequence was identified by Tan and Chew and the protein sequence entered in NCBI as ABL09307 in 2006. should be added. It is "unusual" that the Eriksson manuscript did not show the cDNA as they report a full length aa sequence. But in the paper teh entire 130 aa is present except "X" for the first (2nd) aa. Therefore I am adding the full length sequence of Tan and Chew. on 30 July 2014