ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Mac i 1
Lineage: Source: Plantae Magnoliopsida
Order: Proteales
Species: Macadamia integrifolia (Macadamia)
Biochemical name:Vicilin
MW(SDS-PAGE):50 kDa
Allergenicity:Sera of 8 Macadamia nut allergic subjects were tested for IgE binding to purified natural protein by ELISA and four were positive. The protein was confirmed by LC-MSMS. There is a Pro-peptide of ~ 179 AA, and the mature peptide from 180-625 AA. The submitters indicate the protein is glycosylated, but the glycan does not bind IgE, the protein does.
Route of allergen exposure:Food
Date Created:2020/8/25
Last Updated:2020-08-26 01:21:47
Submitter Info:
Name:Stefan Kabasser; Merima Bublin
Institution:Medical University of Vienna, Institute of Pathophysiology and Allergy Research
City:Vienna, Austria
Email:stefan.kabasser@meduniwien.ac.at
Submission Date:2020-08-06

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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Mac i 1.0101 AAD54246.1Q9SPL3