ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Tyr p 7
Lineage: Source: Animalia Arthropoda
Order: Astigmata
Species: Tyrophagus putrescentiae (Storage mite)
Biochemical name:Bactericidal permeability increasing protein
MW(SDS-PAGE):25 kDa
Allergenicity:298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT to recombinant protein. IgE binding tested by ELISA to recombinant protein, cloned by PCR. Indirect basophil activation was tested. 40 of 298 were positive in IgE binding by ELISA, 38 of 106 were positive by SPT and 22 of 28 were positive by Basophil activation.
Allergenicity reference:32887361
Route of allergen exposure:Airway
Date Created:2020/9/8
Last Updated:2020-09-08 22:20:35
Submitter Info:
Name:En-Chih Liao
Institution:Mackay Medical College
City:Taipei City, Taiwan
Email:enchih@mmc.edu.tw
Submission Date:2020-08-26

Comments

Posted: 08 Sep 2020

Sequences originally by FT Chew but not published. PCR Cloning by Liao, but sequences not confirmed in publication, only in submission

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Tyr p 7.0101DQ983314ABM53750