ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Aed a 12
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Diptera
Species: Aedes aegypti (Yellow fever mosquito)
Biochemical name:Triosphosphate isomerase
MW(SDS-PAGE):23 kDa
Allergenicity:Seven of 19 subjects with allergy and rhinitis to house dust mite and/or cockroach or shrimp were tested for by SPT to whole body extract of Aedes aegypti mosquito. When their sera were tested by ELISA to recombinant protein, with the seven having positive IgE binding by ELISA out of the 19. Five negative controls did not have binding to this ELISA. This data suggests IgE sensitization and possible allergy. Exposure may be by injection or may be by inhalation
Route of allergen exposure:Injection
Date Created:2022/04/17
Last Updated:2022-05-08 23:41:40
Submitter Info:
Name:Jose F Cantillo; Enrique Fernandez-Caldas
Institution:Inmunotek, SL
City:Aldala de Henares, Spain
Email:jfcantillo@inmunotek.com; efcaldas@inmunotek.com
Submission Date:2022-03-10

Comments

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Aed a 12.01XM_001655536.2 Q17HW3