Allergen Details:
| Allergen name: | Ory c 2 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Chordata Order: Lagomorpha Species: Oryctolagus cuniculus (Rabbit) |
| Biochemical name: | Odorant binding protein 2; member of the lipocalin family |
| MW(SDS-PAGE): | 18 kDa (SDS-PAGE, non-red.), 22 kDa (SDS-PAGE red.), 16,351 Da (MALDI-MS) |
| Allergenicity: | Sera from 28 patients allergic to rabbit (symptoms, SPT, sIgE) were tested by ELISA with purified natural and recombinant Ory c 2. Of those, 20 and 21 (71% and 75%) had IgE to the natural and recombinant allergen, respectively, with a high correlation (r = 0.98) between both values. nOry c 2 activated basophils from all 3 tested patients. |
| Route of allergen exposure: | Airway |
| Date Created: | 2022-04-26 |
| Last Updated: | 2022-04-26 14:03:43 |
| Submitter Info: | |
| Name: | Christiane Hilger; Stephanie Kler |
| Institution: | Luxembourg Institute of Health, Department of Infection and Immunity |
| City: | Esch-sur-Alzette, Luxembourg |
| Email: | christiane.hilger@lih.lu; stephanie.kler@lih.lu |
| Submission Date: | 2022-04-08 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Ory c 2.0101 | ON098933 |