WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Act d 6
Lineage: Source: Plantae Magnoliopsida
Order: Ericales
Species: Actinidia deliciosa (Green Kiwi fruit)
Biochemical name:Pectin methylesterase inhibitor
Allergenicity:IgE prevalence: 72% of 50 kiwi allergic patients
Route of allergen exposure:Food
Date Created:Dec 18 2007 2:12PM
Last Updated:2010-04-29 23:57:55
Submitter Info:
Submission Date:


Posted: 10 Sep 2014

Although we (IUIS) list pectin methylesterase inhibitor as allergen Act d 6, with a comment of 72% prevalence of IgE binding by kiwi allergic subjects, the is no record of such a publication and the IUIS records are incomplete. As reported by Bublin et al., 2011, Clin Exp Allergy 41:129-136, they did not detect any individual serum sample as having specific IgE binding to Act d 6 using sera from approximately 200 kiwi allergic subjects. Therefore the relevance of this protein as an allergen is questioned. 10 Sept. 2014 REG

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Act d 6.0101AB091088.1BAC54964P83326