Allergen Details:
Allergen name: | Can f 1 |
---|---|
Allergen source: |
Major taxonomic group: Animalia Chordata Order: Carnivora Species: Canis familiaris (C. lupus familiaris) (Domestic dog) |
Obsolete name: | Dog 1, Ag13 |
Biochemical name: | Lipocalin |
MW(SDS-PAGE): | 23-25 kDa |
Allergenicity: | > 90% of dogallergic patients show IgE binding in RAST; >90% of patients pos. in SPT; IgE a-Can f1/a-dogdander=70%; 15 out of 20 patients (75%) bind rCan f 1, and rCan f 1 gives cross-linking of IgE and histamine release from peripheral blood leucocytes in vitro. |
Allergenicity reference: | PubMed:1863894 |
Route of allergen exposure: | Airway |
Date Created: | 05-02-2003 |
Last Updated: | 2020-05-13 23:58:15 |
Submitter Info: | |
Name: | Carslen Schou |
Institution: | ALK Research |
City: | Horsholm, Denmark |
Email: | |
Submission Date: |
Comments
Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
---|---|---|---|---|
Can f 1.0101 | AF027177 | AAC48794 | O18873 |