WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Cas s 8
Lineage: Source: Plantae Magnoliopsida
Order: Fagales
Species: Castanea sativa (Chestnut)
Biochemical name:Non-specific lipid transfer protein type 1
MW(SDS-PAGE):12-13 (non-red)
Allergenicity:Purified Cas s 8 was recognized on immunblot by IgE in a pool of sera from six patients allergic to apple and peach. Cas s 8 specific IgE levels in this serum pool: 18 RAST Units/mL
Allergenicity reference:10998016
Route of allergen exposure:Food
Date Created:20-03-2003
Last Updated:2015-02-05 18:14:20
Submitter Info:
Submission Date:


Posted: 02 Nov 2014

The N-terminal sequence listed in the publication by Diaz-Perales et al., 2000, and shown in the IUIS submission, does not match any other known sequence in NCBI at more than 57% identity. It is not clear if this sequence represents a natural chestnut LTP protein.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cas s 8.0101