ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Chi t 4
Lineage: Source: Animalia Arthropoda
Order: Diptera
Species: Chironomus thummi thummi (Midge)
Obsolete name:Chi t I
Biochemical name:Hemoglobin, component IIIA
MW(SDS-PAGE):16
Allergenicity:Of 86 subjects with IgE against C.thummi thummi larvae, 76 had IgE against Chi t I, which comprises 12 homologous hemoglobins (Chi t 1-9). 56 of these 76 people were symptomatic. Chi t I induced histamine release in basophils of all 20 patients tested, and acute rhinitis and/or asthmatic reactions in all 25 patients tested in inhalation challenge test.
Allergenicity ref.:1701849
Food allergen:No
Date Created:2003-05-22 12:00:00
Last Updated:2012-08-30 09:17:41
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Table of IsoAllergens:

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Chi t 4.0101 P02231P02231