ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Alt a 1
Lineage: Source: Fungi Ascomycota
Order: Pleosporales
Species: Alternaria alternata (Alternaria plant rot fungus)
MW(SDS-PAGE):16.4 and 15.3 band (30 non-red)
Allergenicity:- Of 57 sera from A. alternaria-sensitive patients, 46 (82%) showed IgE binding to rAlt a 1 on immunoblot. - IgE binding (serumpool, n=34) to A. alternaria extract in ELISA could be inhibited up to 70% by purified native Alt a 1: medline 22659252. - 6 out of 7 patients gave positive skin reactions in response to Alt a 1: medline 22097420 - IgE epitope mapping: medline 22555437
Allergenicity ref.:8957113
Food allergen:No
Date Created:2009-09-25 12:00:00
Last Updated:2010-04-29 16:57:55
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Table of IsoAllergens:

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Alt a 1.0101U82633 U86752AAB40400 AAB47552P79085 
Alt a 1.0102AY568627AAS75297Q6Q128