Allergen Details:
| Allergen name: | Cry j 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Pinopsida Order: Cupressales Species: Cryptomeria japonica (Sugi, Japanese cedar) NCBI Taxomony ID: 3369 |
| Biochemical name: | Pectate lyase |
| MW(SDS-PAGE): | 41-45 kDa (45-50 kDa non-red) |
| Allergenicity: | >90% of 145 sera from CJ pollinosis patients reacted with purified Cry j 1 in ELISA. Dose-dependent histamine release in 2 patients tested. - 12 out of 14 sera from patients with Japanese cedar pollinosis reacted with Cry j 1 in IgE ELISA: medline 90342988. - Purified allergen gives positive skin responses in intradermal skin test: medline 83109936. |
| Allergenicity reference: | PubMed:8564723 |
| Route of allergen exposure: | Airway |
| Date Created: | 27-03-2003 |
| Last Updated: | 2019-08-03 00:43:49 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Cry j 1.0101 | D26544 | BAA05542 | P18632 | |
| Cry j 1.0102 | D26545 | BAA05543 | P18632 | |
| Cry j 1.0103 | D34639 | BAA07020 | P18632 | |
| Cry j 1.0103 | AB081309 | BAB86286 | Q8RUR1 | |
| Cry j 1.0103 | AB081310 | BAB86287 | Q8RUR1 |