ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Equ c 2
Lineage: Source: Animalia Chordata
Order: Perissodactyla
Species: Equus caballus (Domestic horse)
Obsolete name:AL21 horse
Biochemical name:Lipocalin
MW(SDS-PAGE):17 kDa
Allergenicity:IgE binding in immunoblot (11 of 23 patients tested); 33.3% of 21 horse sensitized patients tested showed IgE binding to Equ c 2. See also medline 98237590 March 2020, 20 or 22 of 35 subjects allergic to horse dander were positive in IgE binding to recombinant and natural protein preparations using ImmunoCAP
Allergenicity reference:9686871
Route of allergen exposure:Airway
Date Created:05-02-2003
Last Updated:2020-03-26 19:47:36
Submitter Info:
Name:Vincent Bulone; Jonas Lidholm
Institution:Centre de Techerches sur les Macromolecules Vegetales; Thermo Fisher Scientific R&D
City:Grenoble cedex 9, France; Uppsala, Sweden
Email:bulone@cermav.cnrs.fr; jonas.lidholm@thermofisher.com
Submission Date:2003-01-02

Comments

Posted: 26 Mar 2020

Scientists at Thermofisher have isolated and characterized a full length Equ c 2 which is replacing the two partial peptide sequences that were named Equ c 2.0101 and 2.0102 based on peptides, which both had gaps.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Equ c 2.0101MG761768AYL64456  
Equ c 2.0102 P81217P81217