WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Fel d 1
Lineage: Source: Animalia Chordata
Order: Carnivora
Species: Felis domesticus (cat)
Obsolete name:cat-1
Biochemical name:Uteroglobin (chain 1)
MW(SDS-PAGE):14 and 4
Allergenicity:- >90% decrease in skin-test reactivity in cat-allergic patients was found after absorption of Fel d 1 from catdander extract. In RAST, a 76% reduction of IgE binding was found after depletion of Fel d 1 (medline 89054671). - recombinant chain 1 and chain 2: IgE binding in ELISA (medline 93254448) - IgE binding to nFel d 1 and rFel d 1 (medline 22304954)
Allergenicity reference:824067
Route of allergen exposure:Unknown
Date Created:05-02-2003
Last Updated:2010-04-29 23:57:55
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Fel d 1.0101M74952 (chain 1) M77341 (chain 2)AAC37318 (chain 1) AAC41616 (chain 2)P30438 (chain 1) P30440 (chain 2)1PUO