Allergen Details:
| Allergen name: | Fra a 3 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Rosales Species: Fragaria ananassa (Strawberry) NCBI Taxomony ID: 3747 |
| Biochemical name: | Non-specific lipid transfer protein type 1 (nsLTP1) |
| MW(SDS-PAGE): | 9 kDa |
| Allergenicity: | 28 strawberry allergic subjects were tested for IgE binding to proteins from strawberries. 16 of 17 had pollen allergy as well, 4 of 5 were DBPCFC to strawberry. Five of 17 were IgE positive to rFra 3 by RAST and confirmed by immunoblot (8 were +). Two IgE positive sera were tested using Basophil histamine release and were positive. |
| Allergenicity reference: | PubMed:16650053 |
| Route of allergen exposure: | Food |
| Date Created: | 13-10-2006 |
| Last Updated: | 2019-08-17 02:42:53 |
| Submitter Info: | |
| Name: | L. Zuidmeer; EMJ Salentijn; R van Ree |
| Institution: | Amsterdam Medical Centre |
| City: | Amsterdam, The Netherlands |
| Email: | r.vanree@amc.uva.nl |
| Submission Date: | 2006-12-01 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Fra a 3.0101 | AJ315844 | CAC86258 | Q8VX12 | |
| Fra a 3.0102 | DQ066728 | AAY83342 | Q4PLT9 | |
| Fra a 3.0201 | DQ066727 | AAY83341 | Q4PLU0 | |
| Fra a 3.0202 | DQ066731 | AAY83345 | Q4PLT6 |