Allergen Details:
| Allergen name: | Jun a 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Pinopsida Order: Cupressales Species: Juniperus ashei (Mountain cedar) NCBI Taxomony ID: 13101 |
| Obsolete name: | Juniperus sabinoides synon. Jun s 1 |
| Biochemical name: | Pectate lyase |
| MW(SDS-PAGE): | 43 kDa |
| Allergenicity: | 10 out of 14 (71.4% of sera from mountain cedar-allergic patients showed IgE binding to purified Jun a 1 in ELISA. rJun a 1 was recognized on immunoblot by IgE of a serumpool from cedar-sensitive patients. |
| Allergenicity reference: | PubMed:10482835 PubMed:725536 |
| Route of allergen exposure: | Airway |
| Date Created: | 02-04-2003 |
| Last Updated: | 2019-08-28 22:39:09 |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Jun a 1.0101 | AF106662 | AAD03608 | P81294 | |
| Jun a 1.0102 | AF106663 | AAD03609 | P81294 |
January 2017, the taxonomy of Juniperus sabinoides is not a valid name and the common name, location and protein matches Juniperus ashei, Jun a 1. There were only 5 amino acids described for Jun s 1 and they match segments in the Pectate lyases in Jun a 1 and Jun v 1. Therefore the Jun s 1 name is moved to Jun a 1 as a synon. in the WHO/IUIS database.