ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Sola l 1
Lineage: Source: Plantae Magnoliopsida
Order: Solanales
Species: Solanum lycopersicum (Lycopersicon esculentum) (Tomato)
Obsolete name:Lyc e 1
Biochemical name:Profilin
MW(SDS-PAGE):14
Allergenicity:Eleven out of 34 food-allergic patients (32%) display IgE binding to both purified profilins. Preincubation of a serum pool with either purified rCap a 2 or rSola l 1 nearly abolished IgE binding to natural Cap a 2 and Sola l 1, respectively. In addition, purified recombinant Cap a 2 was able to inhibit IgE-binding to rSola l 1 by approximately 50%, whereas rSola l 1 completely blocked IgE-binding to rCap a 2 in cross-inhibition assays.
Allergenicity reference:12915767
Route of allergen exposure:Food
Date Created:08-08-2003
Last Updated:2013-03-05 20:26:42
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Sola l 1.0101AJ417553CAD10377Q93YG7