WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Ory s 12
Lineage: Source: Plantae Liliopsida
Order: Poales
Species: Oryza sativa (Rice)
Biochemical name:Profilin A
Allergenicity:IgE binding was tested to extracts and recombinant proteins from Hirano et al., 2013, J Biochem. The 10 subjects sera from Japan were tested positive to beta expansin and polycalcin extensin and weakly to polygalacturonase, almost negative to profilin. The clones were expressed as fusion proteins with thioredoxin and the three subjects with IgE binding to fused recombinant protein were nearly all due to thioredoxin. Those without IgE to thioredoxin did not bind. The significance of the three binding to fused thioredoxin and profilin is therefore not clear.
Allergenicity reference:23694780
Route of allergen exposure:Airway
Date Created:
Last Updated:2018-12-14 21:00:25
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Ory s 12.0101AF310253AAG32056Q9FUD1