WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Per a 1
Lineage: Source: Animalia Arthropoda
Order: Blattodea
Species: Periplaneta americana (American cockroach)
Obsolete name:Cr-PII
Biochemical name:major allergen Per a 1.0101, nitrile-specifier
Allergenicity:- Of 35 allergic patients, 22 had a positive skin test to CR-extract and Per a 1. Of these 22 patients, 12 (54.4%) showed a positive skin reaction to rPer a 1. IgE Ab binding to rPer a 1 was demonstrated in ELISA. - Amino acid sequences 78LIRALFGL85 and 267IRSWFGLP1274 of the American cockroach Per a 1.0104 allergen were involved in IgE binding, as measured by ELISA. 80%-100% of the sera tested showed IgE binding to these peptides: medline 22302513.
Allergenicity reference:10221434
Route of allergen exposure:Airway
Date Created:16-05-2003
Last Updated:2019-01-17 00:17:56
Submitter Info:
Submission Date:


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Per a 1.0101AF072222AAD13533Q9TZR6 
Per a 1.0102U78970AAC34312O18535 
Per a 1.0103U69957AAB82404O18530 
Per a 1.0104U69261AAC34737O18528 
Per a 1.0201U69260AAC34736O18527