ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Phl p 4
Allergen source: Major taxonomic group: Plantae Liliopsida (monocots)
Order: Poales
Species: Phleum pratense (Timothy)
NCBI Taxomony ID: 15957
Biochemical name:Berberine bridge enzyme
MW(SDS-PAGE):55 kDa
Allergenicity:82% of patients tested showed IgE binding to 60 kd Phl p 4 proteins on immunoblot of ragweed pollen extract. IgE binding to nitrocellulose-blotted ragweed pollen extract was inhibited with purified Phl p 4 (2 patients tested) - 75% of grass pollen-allergic patients show IgE binding to Phl p 4 on immunoblot of timothy grass pollen extract. See also medline 96316935
Allergenicity reference:PubMed:1597349
Route of allergen exposure:Airway
Date Created:13-02-2003
Last Updated:2019-09-05 22:45:03
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Phl p 4.0101AJ512487CAD54670Q5ZQK5 
Phl p 4.0201AJ512488CAD54671Q5ZQK4