ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Pyr c 4
Lineage: Source: Plantae Magnoliopsida
Order: Rosales
Species: Pyrus communis (Pear)
Biochemical name:Profilin
MW(SDS-PAGE):14
Allergenicity:Cross-reactivity with Bet v 2 (birch pollen profilin): 43 of 49 patients (88%), preselected for an IgE-reactivity with Bet v 2 showed specific IgE-antibodies to rPyr c 4. Positive in cellular mediator release test.
Allergenicity reference:11419723
Route of allergen exposure:Food
Date Created:24-04-2003
Last Updated:2010-04-29 23:57:55
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Pyr c 4.0101AF129424AAD29410Q9XF38