ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Pyr c 4
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Rosales
Species: Pyrus communis (Pear)
NCBI Taxomony ID: 23211
Biochemical name:Profilin
MW(SDS-PAGE):14 kDa
Allergenicity:Cross-reactivity with Bet v 2 (birch pollen profilin): 43 of 49 patients (88%), preselected for an IgE-reactivity with Bet v 2 showed specific IgE-antibodies to rPyr c 4. Positive in cellular mediator release test.
Allergenicity reference:PubMed:11419723
Route of allergen exposure:Food
Date Created:24-04-2003
Last Updated:2019-09-07 02:30:39
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Pyr c 4.0101AF129424AAD29410Q9XF38