ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Lip b 1
Lineage: Source: Animalia Arthropoda
Order: Psocoptera
Species: Liposcelis bostrychophila (Booklouse)
Biochemical name:unknown function
MW(SDS-PAGE):26 kDa
Allergenicity:12 of 33 booklice sensitized individuals with allergic asthma had IgE that reacted with a 26 kDa band by 1D blots of extracts (natural Lip b 1) and a pool of three subjects had IgE to the protein identified by sequencing from 2 dimensional immunoblots, with 24 amino acids.
Allergenicity ref.:22123223
Food allergen:No
Date Created:2014-11-13 12:00:00
Last Updated:2016-10-11 12:38:21
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Comments

Posted: 13 Nov 2014

This 24 amino acid peptide (Fukutomi et al., 2012) is unique in NCBI and there are no highly similar proteins identified by BLAST.

Posted: 03 Nov 2016

Osamu Ishibashi submitted in September, 2016. Numbe Lip b 1.0101 has a 100% match to the 24 mer identified by Fukutomi and accepted by IUIS in 2012. the full length sequence will be shown in 2017.

Table of IsoAllergens:

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Lip b 1.0101 P86712P86712 
Lip b 1.0101LC177784 (to be released in January 2017)P86712P86712 
Lip b 1.0102LC177783P86712 but with 3 mismatches