ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Ara h 2
Lineage: Source: Plantae Magnoliopsida
Order: Fabales
Species: Arachis hypogaea (Peanut, groundnut)
Biochemical name:Conglutin (2S albumin)
MW(SDS-PAGE):17
Allergenicity:- Of 40 peanut-allergic patients tested, 34 (85%) showed IgE binding to rAra h 2 on immunoblot. - In ELISA of partially purified Ara h 2, all 6 peanut-allergic patients tested had IgE Ab against Ara h 2: medline 93094482. - IgE binding epitopes: medline 22092281 and medline 97330026
Allergenicity ref.:10474031 918645
Food allergen:Yes
Date Created:27-10-2003
Last Updated:2018-08-21 21:08:49
Submitter Info:
Name:JS Stanley
Institution:University of Arkansas
City:Little Rock, AR, USA
Email:

Comments

Posted: 21 Aug 2018

A number of laboratories contributed to sequencing and allergenicity of the the 2S albumins from peanut, called Ara h 2. The AW Burks lab in Arkansas, Wolf-Becker's lab in Germany, the Chatel lab INRA, in France and the Visquez group in Alabama among others. We do not have a record of the original submission.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Ara h 2.0101AY007229AAK96887  
Ara h 2.0201AY158467AAN77576Q6PSU2-1