ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Ara h 16
Lineage: Source: Plantae Magnoliopsida
Order: Fabales
Species: Arachis hypogaea (Peanut, groundnut)
Biochemical name:non-specific Lipid Transfer Protein 2
MW(SDS-PAGE):8.5 by SDS PAGE reducing
Allergenicity:IgE binding to the native protein by RAST, with 4 positive out of 25 clinically proven peanut allergic subjects
Food allergen:Yes
Date Created:2015-05-22 12:00:00
Last Updated:2016-10-11 13:10:26
Submitter Info:
Name:Rob Aalberse, Peter Briza (Salzburg), Ninotska Derksen and Theo Rispens (Amsterdam)
Institution:Sanquin Blood Supply & University of Amsterdam
City:Amsterdam, The Netherlands
Email:r.aalberse@sanquin.nl
Date:2015-05-21

Comments

Posted: 21 May 2015

Provissionally accepted pending on IUIS meeting at EAACI, 2015. Native peanut LTP was isolated with mass measured by MS, no glycosylation. Denovo peptide sequencing provided the 7kDa protein sequence, with lower case aa indicating not 100% certain. The protein is 60% identical with Api g 6.

Table of IsoAllergens:

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Ara h 16.0101