ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

Member Login

Allergen Details:

Allergen name: Per a 11
Lineage: Source: Animalia Arthropoda
Order: Blattodea
Species: Periplaneta americana (American cockroach)
Biochemical name:alpha amylase
MW(SDS-PAGE):55 kDa
Allergenicity:Sera from 39 of 40 (83%) patients reacted to Per a 11 on immunoblots. ELISA inhibition of serum IgE reactivity to the cockroach midgut extract (CME) using purified Per a 11 was significant (60%). Twelve of 15 (80%) cockroach-allergic patients had positive SPT reactions to Per a 11. In comparison with healthy control, Per a 11 at 1.0 μg/ml induced approximately up to 5.8-fold increase in the number of CD63 and CCR3 double-positive cells following incubating it with PBMC from patients with cockroach allergy
Food allergen:No
Date Created:2015-11-10 12:00:00
Last Updated:2016-10-11 12:57:36
Submitter Info:
Name:Su An
Institution:Kunming Institute of Zoology, Chinese Academy of Sciences
City:Kunming, China
Email:aslxj@mail.ustc.edu.cn
Date:2015-05-05

Comments

Table of IsoAllergens:

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Per a 11.0101KR019685AKH04310