ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Jug r 5
Lineage: Source: Plantae Magnoliopsida
Order: Fagales
Species: Juglans regia (English walnut)
Biochemical name:PR-10
MW(SDS-PAGE):20 kDa
Allergenicity:Based on case history of allergy to English walnut, for those with + IgE binding by ImmunoCAP to recombinant E. coli produced protein (Walnut specific Immunocap to PR-10) and SPT (used Alyostal, Stallergens). Food challenges with DBPCFC 9 positive, open food challenge, 5 positive were both done using raw walnut from a local food market. seems to be due to primary sensitization to birch pollen allergy. But they have evidence this PR-10 is expressed in the nut and it was able to inhibit bindign to a 20 kDa IgE binding band in walnut extract.
Food allergen:Yes
Date Created:2016-06-26 12:00:00
Last Updated:2016-10-11 13:13:00
Submitter Info:
Name:Andrea Wangorsch
Institution:Paul Ehrlich Institute
City:Langen, Germany
Email:andrea.wangorsch@pei.de
Date:2016-04-19

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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Jug r 5.0101KX034087.1APD76154.1