WHO/IUIS Allergen Nomenclature Sub-Committee

Member Login

Allergen Details:

Allergen name: Cup s 2
Lineage: Source: Plantae Pinopsida
Order: Cupressales
Species: Cupressus sempervirens (Common cypress)
Biochemical name:Polygalacturonase
Allergenicity:sera from 19 of 31 subjects with airway allergy in areas exposed to Common cypress (Curessus sempervirens) were positive to a 43 kDa protein based on immunoblots. The protein was characterized and demonstrated to be highly identical to Jun a 2 (~95% identity) and to Cha o 2 (80%).
Food allergen:No
Date Created:2017-01-11 16:03:09
Last Updated:2017-01-11 16:03:09
Submitter Info:
Name:Pascal Ponset
Institution:Institut Pasteur
City:Paris, France


Posted: 11 Jan 2017

Ten reads of LC-MSMS produced 33 overlapping peptides with high identity match to a homologous protein from Cupressus arizonica and to Juniperus ashei, with >74% coverage. Edmand degradation was used to identify the N-terminus. That sequence was submitted to UniProt as C0HKB1, which is not yet posted.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cup s 2.0101  C0HKB1