ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Per a 5
Lineage: Source: Animalia Arthropoda
Order: Blattodea
Species: Periplaneta americana (American cockroach)
Biochemical name:Gluthathione S-transferase
MW(SDS-PAGE):23 kDa
Allergenicity:Positive IgE tests with 15 of 15 cockroach allergic patients showing positive binding to natural and recombinant protein, with negative responses from 5 of 5. IgE binding tested by dot blot and ELISA. Subjects positive by SPT. NOTE:this submission was from Thailand in 2017, there was a previous paper by Wei et al., 2014 that showed IgE binding and basophil activity to a 98% identical sequence that Wei called Per a 5. That is now added as Per a 5.0102.
Route of allergen exposure:Unknown
Date Created:
Last Updated:2017-12-21 21:25:03
Submitter Info:
Name:Nitat Sookrung
Institution:Faculty of Medicine, Siriraj Hospital, Mahidol University Dept. of Research
City:Bangkok, Thailand
Email:nitat.soo@mahidol.ac.th
Submission Date:2017-10-02

Comments

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Per a 5.0101MG255130   
Per a 5.0102 AEV23867.1