ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Ole e 12
Lineage: Source: Plantae Magnoliopsida
Order: Lamiales
Species: Olea europaea (Olive)
Biochemical name:Isoflavone reductase
MW(SDS-PAGE):37 kDa
Allergenicity:Twenty two patients out of 63 recruited with peach allergy also had olive pollen sensitization. These were tested for IgE binding to recombinant E. coli produced protein by ELISA. Earlier work had shown IgE binding to this protein from a different subject as early as 2008. Natural protein was also purified and proteomics demonstrated it was the same protein and had IgE binding in 2D gel blots.
Allergenicity reference:26391188
Route of allergen exposure:Unknown
Date Created:
Last Updated:2018-04-04 18:32:54
Submitter Info:
Name:Maria Teresa Villalba, Lourdes Castro
Institution:Comlutense University of Madrid Biochemistry, ALK-Abello
City:Madrid, Spain
Email:mvillalb@ucm.es, lourdes.castro@alk.net
Submission Date:2018-03-02

Comments

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Ole e 12.0101EU927297.1ACL13551.1E1U332