ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Pan h 2
Lineage: Source: Animalia Chordata
Order: Siluriformes
Species: Pangasianodon hypophthalmus (Striped catfish)
Biochemical name:beta-enolase
MW(SDS-PAGE):50 kDa
Allergenicity:80 subjects with food allergy to striped catfish, Pangasianodon hypophthalmus, were tested by SPT with muscle of this species in saline buffer and 61 were found to have > 5 mm weal. IgE binding to proteins were tested by SDS-PAGE reducing blots and the protein at the identified band was identified by LC-MSMS with 89% coverage compared to genomic predicted protein by quantitative assessment. 18 subjects had positive binding. 10 controls were negative and the other 62 of the fish allergic subjects were negative.
Route of allergen exposure:Food
Date Created:23/07/2019
Last Updated:2019-09-17 00:22:54
Submitter Info:
Name:Thimo Ruethers; Andreas Lopata
Institution:James Cook University
City:Townsville, Australia
Email:thimo.ruethers@myjcu.edu.au; andreas.lopata@jcu.edu.au
Submission Date:2019-07-23

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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Pan h 2.0101XM_026921449.1XP_026777250.1