Allergen Details
| Allergen name: | Aes h 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Sapindales Species: Aesculus hippocastanum (Horse chestnut) NCBI Taxomony ID: 43364 |
| Biochemical name: | Defensin-like protein |
| MW(SDS-PAGE): | 5.8 kDa |
| Allergenicity: | Thirty mugwort pollen-sensitized patients sensitized to horse chestnut seeds as determined by prick-to-prick test were included in the study. Four of those showed allergic reactions upon contact with horse chestnuts. All 30 sera reacted to rAes h 1 and 29 to nAes h 1 in an IgE-ELISA. Inhibition ELISA showed cross-reactivity with Art v 1 from mugwort pollen and suggested Art v 1 to be the initial sensitizer. |
| Allergenicity reference: | DOI:10.1111/all.16335 |
| Route of allergen exposure: | Contact |
| Created: | 2020-03-25 20:54:26 |
| Last Updated: | 2024-09-24 11:34:08 |
| Submitter Info: | |
| Name: | Gabriele Gadermaier |
| Institution: | University of Salzburg |
| City: | Salzburg, Austria |
| Email: | gabriele.gadermaier@sbg.ac.at |
| Submission Date: | 2020-01-31 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Aes h 1.0101 | Q7M1F3 | 1BK8 |