WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Phl p 3
Allergen source: Major taxonomic group: Plantae Liliopsida (monocots)
Order: Poales
Species: Phleum pratense (Timothy)
NCBI Taxomony ID: 15957
Biochemical name:Group 3 grass pollen allergen; comtains a C-terminal expansin domain
MW(SDS-PAGE):10.9 kDa
Allergenicity:70 grass pollen allergic subjects sera were tested from Germany, by western blot. 57% bound to Phl p 1, 2 and 3. They designated two proteins, 3.0101 and 3.0102, with 3 AA differences D20N, S88K, K94T. No glycosylation sites, no Cysteines. Accession AY421969 as 3.0101. Antibodies to Phl p 2 and Phl p 3 were somewhat cross-reactive. They are 57% identical. Basophil activity was shown similar for 3 patients for Phl p 2 and Phl p 3.
Allergenicity reference:PubMed:16776686
Route of allergen exposure:Airway
Date Created:2020/06/17
Last Updated:2022-04-29 16:12:08
Submitter Info:
Name:Petersen, A
Institution:Molecular and Clinical Allergology, Research Center Borstel
City:Borstel, Germany
Submission Date:2020-06-17


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Phl p 3.0101AY421969AAR31142Q69B422JNZ 3FT1 3FT9