WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Mac i 1
Allergen source: Major taxonomic group: Plantae basal Mesangiosperms
Order: Proteales
Species: Macadamia integrifolia (Macadamia)
NCBI Taxomony ID: 60698
Biochemical name:Vicilin
Allergenicity:Sera of 8 Macadamia nut allergic subjects were tested for IgE binding to purified natural protein by ELISA and four were positive. The protein was confirmed by LC-MSMS. There is a Pro-peptide of ~ 179 AA, and the mature peptide from 180-625 AA. The submitters indicate the protein is glycosylated, but the glycan does not bind IgE, the protein does.
Allergenicity reference:PubMed:34525424
Route of allergen exposure:Food
Date Created:2020/8/25
Last Updated:2023-03-28 17:52:25
Submitter Info:
Name:Stefan Kabasser; Merima Bublin
Institution:Medical University of Vienna, Institute of Pathophysiology and Allergy Research
City:Vienna, Austria,
Submission Date:2020-08-06


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Mac i 1.0101 AAD54246.1Q9SPL3 
Mac i 1.0101 (28-76) AAD54245.1Q9SPL4