WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Tyr p 7
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Tyrophagus putrescentiae (Storage mite)
NCBI Taxomony ID: 59818
Biochemical name:Bactericidal permeability increasing protein
Allergenicity:298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT to recombinant protein. IgE binding tested by ELISA to recombinant protein, cloned by PCR. Indirect basophil activation was tested. 40 of 298 were positive in IgE binding by ELISA, 38 of 106 were positive by SPT and 22 of 28 were positive by Basophil activation.
Allergenicity reference:PubMed:32887361
Route of allergen exposure:Airway
Date Created:2020/9/8
Last Updated:2020-09-08 22:20:35
Submitter Info:
Name:En-Chih Liao
Institution:Mackay Medical College
City:Taipei City, Taiwan
Submission Date:2020-08-26


Posted: 08 Sep 2020

Sequences originally by FT Chew but not published. PCR Cloning by Liao, but sequences not confirmed in publication, only in submission

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Tyr p 7.0101DQ983314ABM53750