WHO/IUIS Allergen Nomenclature Sub-Committee

Financial contributions from IUIS, EAACI, and AAAAI

Member Login

Allergen Details:

Allergen name: Tyr p 20
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Tyrophagus putrescentiae (Storage mite)
NCBI Taxomony ID: 59818
Biochemical name:Arginine kinase
Allergenicity:298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT and ELISA to recombinant Tyr p 20.0101, which had been cloned by PCR. Indirect basophil activation was tested. 51 of 298 were positive for IgE binding by ELISA, 45 of 106 were positive by SPT and 25 of 30 positive by basophil activation.
Allergenicity reference:PubMed:32887361
Route of allergen exposure:Airway
Date Created:2020/9/8
Last Updated:2022-04-13 16:29:32
Submitter Info:
Name:En-Chih Liao
Institution:Mackay Medical College
City:Taipei City, Taiwan
Submission Date:2020-08-26


Posted: 13 Sep 2020

cDNA sequence and predicted AA sequence in submission. Not for public view until published. High identity to Der p 20, Blo t 20. two peptides of recombinant protein determined by LC-MSMS.

Posted: 11 Oct 2022

The sequence of Tyr p 20.0201 was updated on 2022-10-11. The originally submitted sequence had an N-terminal extension due to an incorrectly identified start codon.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Tyr p 20.0101MT900252QOI58528A0A868BHP5 
Tyr p 20.0201MZ824392UXW65972