WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Cari p 2
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Brassicales
Species: Carica papaya (Papaya)
NCBI Taxomony ID: 3649
Biochemical name:Chymopapain; member of the papain-like cysteine protease (petidase C1) family
Allergenicity:Ten subjects allergic to ingestion of papaya fruit were tested with recombinant protein produced by a cDNA clone from EMBL accession X97789.1, Taylor et al., protein is in GEPEPT as CAA66378.1. The recombinant protein was characterized also with LC-MSMS on the N-terminus. The rProtein was used for SPT in patients with 3 of 3 testing positive. Also used in a humanized rat basophil leukemia assay and 6 sera were positive.
Route of allergen exposure:Food
Date Created:2020/11/5
Last Updated:2022-05-10 18:43:00
Submitter Info:
Name:Gaurab Sircar; Moumita Bhowmik
Institution:Visva-Bharati University, Dept. of Botany; Bose Institute Div. of Plant Biology
City:Santiniketan, India; Kolkata, India;
Submission Date:2020-09-29


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cari p 2.0101X97789.CAA66378P14080