WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Can s 5
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Rosales
Species: Cannabis sativa (Indian hemp)
NCBI Taxomony ID: 3483
Biochemical name:Pathogenesis-related protein PR-10, Bet v 1-related protein
MW(SDS-PAGE):17.7 kDa
Allergenicity:35 of 45 subjects with allergy to Cannabis (n=25) and/or birch pollen (n=20) were positive in IgE binding tested by cytometric bead assay using recominant protein as the target. Also, 8 of 8 tested by Mast Cell Activation were positive using the same recombinant protein. Subjects also reportedly were positive in contact testing.
Allergenicity reference:PubMed:33607338
Route of allergen exposure:Airway
Date Created:2021/01/24
Last Updated:2022-04-29 16:26:00
Submitter Info:
Name:Hans-Peter Rihs
Institution:IPA, Molecular Genetics
City:Bochum, Germany
Submission Date:2020-11-27


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Can s 5.0101JN6792251AFN42528I6XT51