ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details

Allergen name: Zan b 2
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Sapindales
Species: Zanthoxylum bungeanum (Sichuan pepper)
NCBI Taxomony ID: 328401
Biochemical name:11S globulin seed storage protein; legumin
MW(SDS-PAGE):50 kDa non reducingh, 22.3 kDa reducing
Allergenicity:Six subjects with claimed allergic responses to reduced glycinin of natural 11S albumin of Sichuan pepper were tested and found to have IgE binding to the reduced form of Sichuan pepper. The subjects had IgE binding to 2S albumin of these proteins by western blot and by ELISA Subjects had IgE binding to four proteins, two of similar MW and sequence and two others with IgE binding to compiled 2S albumins.
Allergenicity reference:PubMed:38551197
Route of allergen exposure:Food
Created:2021-07-23 04:33:23
Last Updated:2024-12-06 14:59:13
Submitter Info:
Name:Tengchen Jun, Hong Li
Institution:University of Science and Technology of China; Peking Union Medical College Hospital
City:Hefei, China
Email:jint@ustc.edu.cn; lihong1228sec@163.com
Submission Date:2021-06-09

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Table of Isoallergens

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Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Zan b 2.0101MZ293069QYU76045A0A8G0QCJ5 
Zan b 2.0102MZ293070QYU76046A0A8G0QCB5 
Zan b 2.02MZ293068QYU76044A0A8G0QCW4 
Zan b 2.03MZ333534QYS16039A0A8G0KJM2