WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Ory c 2
Allergen source: Major taxonomic group: Animalia Chordata
Order: Lagomorpha
Species: Oryctolagus cuniculus (Rabbit)
NCBI Taxomony ID: 9986
Biochemical name:Odorant binding protein 2; member of the lipocalin family
MW(SDS-PAGE):18 kDa (SDS-PAGE, non-red.), 22 kDa (SDS-PAGE red.), 16,351 Da (MALDI-MS)
Allergenicity:Sera from 28 patients allergic to rabbit (symptoms, SPT, sIgE) were tested by ELISA with purified natural and recombinant Ory c 2. Of those, 20 and 21 (71% and 75%) had IgE to the natural and recombinant allergen, respectively, with a high correlation (r = 0.98) between both values. nOry c 2 activated basophils from all 3 tested patients.
Route of allergen exposure:Airway
Date Created:2022-04-26
Last Updated:2022-04-26 14:03:43
Submitter Info:
Name:Christiane Hilger; Stephanie Kler
Institution:Luxembourg Institute of Health, Department of Infection and Immunity
City:Esch-sur-Alzette, Luxembourg;
Submission Date:2022-04-08


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Ory c 2.0101ON098933