WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Cor a 16
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Fagales
Species: Corylus avellana (Hazelnut)
NCBI Taxomony ID: 13451
Biochemical name:7S globulin seed storage protein (vicilin) containing N-terminal alpha-hairpinin (vicilin_N) peptides
MW(SDS-PAGE):6-8 kDa and 47.5 kDa
Allergenicity:106 children with suspected hazelnut allergy were tested. All had IgE to hazelnut extract as measured by ImmunoCAP. Of those, 56 (53%) had positive ImmunoCAP to a recombinant protein containing 5 of the 12 N-terminal peptides, while 73 (69%) had IgE to the recombinant mature vicilin (containing only the cupin domains).
Allergenicity reference:PubMed:35851969
Route of allergen exposure:Food
Date Created:2022 05 -06
Last Updated:2022-12-07 13:58:55
Submitter Info:
Name:Jonas Lidholm
Institution:Thermo Fisher Scientific, Research and Development
City:Uppsala, Sweden
Submission Date:2022-04-06


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cor a 16.0101ON060881UTE00286  
Cor a 16.0101 (29-714)ON060881UTE00286 (29-714)  
Cor a 16.0101 (715-1133)ON060881UTE00286 (715-1133)