WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Pla a 6
Allergen source: Major taxonomic group: Plantae basal Mesangiosperms
Order: Proteales
Species: Platanus acerifolia (London plane tree)
NCBI Taxomony ID: 140101
Biochemical name:Enolase
Allergenicity:Thirty-seven P. acerifolia-sensitized patients with allergic rhinitis in spring were tested. All has positive SPT and sIgE (measured by ImmunoCAP) to plane tree pollen extract. Of those 12 (32%) had serum IgE to natural Pla a 6, measured by immunoblot. Eleven of the 12 nPla a 6-reactive sera also recognized recombinant Pla a 6 in immunoblot. In a BAT assay, basophils from 4 of 5 Pla a 6-sensitized patients could be stimulated by nPla a 6.
Allergenicity reference:PubMed:36252468
Route of allergen exposure:Airway
Date Created:2022-08-22
Last Updated:2023-03-31 13:17:17
Submitter Info:
Name:Jin-Lyu Sun, Ji-Fu Wei
Institution:State Key Laboratory of Complex Severe and Rare Diseases, PUMCH, CAMS; Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University
City:Beijing, China and Nanjing, China,
Submission Date:2022-08-05


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Pla a 6.0101OK323202UYQ90943