WHO/IUIS Allergen Nomenclature Sub-Committee

Financial contributions from IUIS, EAACI, and AAAAI

Member Login

Allergen Details:

Allergen name: Hel a 16
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Asterales
Species: Helianthus annuus (Sunflower)
NCBI Taxomony ID: 4232
Biochemical name:2S albumin seed storage protein, SESA20-2
Allergenicity:Sera from 30 subjects were tested. Among them, 17 patients were allergic to sunflower seeds (SFS), with SFS-specific IgE > 0.35 kU/L (ImmunoCAP). Control sera were from 13 patients tolerant to SFS but allergic to other foods. Seven of 17 (41%) SFS-allergic but none of the 13 SFS-tolerant food-allergic patients had IgE to Hel a 16, as measured by ELISA with the natural purified allergen.
Allergenicity reference:PubMed:38619510
Route of allergen exposure:Food
Date Created:2023-06-30
Last Updated:2024-04-16 14:24:04
Submitter Info:
Name:Stéphane Hazebrouck, Hervé Bernard
Institution:French National Research Institute for Agriculture, Food and Environment (INRAE), Université Paris-Saclay
City:Gif-sur-Yvette, France,
Submission Date:2023-05-12


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Hel a 16.0101KR401269ALO17643 (amino acids 164-290)A0A161CT49 (amino acids 164-290)