Allergen Details
| Allergen name: | Pap s 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae basal Mesangiosperms Order: Ranunculales Species: Papaver somniferum (Opium poppy) NCBI Taxomony ID: 3469 |
| Biochemical name: | Vicilin (7S globulin) with N-terminal alpha-hairpinin peptides |
| MW(SDS-PAGE): | 10 kDa, 17 kDa (alpha-hairpinins), 50 kDa (vicilin) |
| Allergenicity: | Pap s 1 is post-traslationally cleaved into N-terminal alpha-hairpinin peptides and the C-terminal mature vicilin. Both parts were separately purified and tested for IgE binding. Therefore, see the isoallergen records for IgE binding data. |
| Allergenicity reference: | PubMed:38734371 |
| Route of allergen exposure: | Food |
| Created: | 2023-08-29 15:16:01 |
| Last Updated: | 2024-05-23 13:17:40 |
| Submitter Info: | |
| Name: | Aleksandra Podzhilkova, Merima Bublin |
| Institution: | Department of Pathophysiology and Allergy Research, Medical University of Vienna |
| City: | Vienna, Austria |
| Email: | aleksandra.podzhilkova@muv.ac.at, merima.bublin@muv.ac.at |
| Submission Date: | 2023-05-11 |
Comments
Table of Isoallergens
Click on the arrows to show the details of individual isoallergens, click on +/- to show/hide the details of all isoallergens.
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Pap s 1.0101 | CM010716 | RZC52308 | A0A4Y7IXT7 | |
| Pap s 1.0101 (27-424) | CM010716 | RZC52308 (residues 27-424) | A0A4Y7IXT7 (residues 27-424) | |
| Pap s 1.0101 (425-846) | CM010716 | RZC52308 (residues 425-846) | A0A4Y7IXT7 (residues 425-846) |