ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Pap s 1
Allergen source: Major taxonomic group: Plantae basal Mesangiosperms
Order: Ranunculales
Species: Papaver somniferum (Opium poppy)
Biochemical name:Vicilin (7S globulin) with N-terminal alpha-hairpinin peptides
MW(SDS-PAGE):10 kDa, 17 kDa (alpha-hairpinins), 50 kDa (vicilin)
Allergenicity:Pap s 1 is post-traslationally cleaved into N-terminal alpha-hairpinin peptides and the C-terminal mature vicilin. Both parts were separately purified and tested for IgE binding. Therefore, see the isoallergen records for IgE binding data.
Route of allergen exposure:Food
Date Created:2023-08-29
Last Updated:2023-08-29 16:00:29
Submitter Info:
Name:Aleksandra Podzhilkova, Merima Bublin
Institution:Department of Pathophysiology and Allergy Research, Medical University of Vienna
City:Vienna, Austria
Email:aleksandra.podzhilkova@muv.ac.at, merima.bublin@muv.ac.at
Submission Date:2023-05-11

Comments

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Pap s 1.0101CM010716RZC52308A0A4Y7IXT7 
Pap s 1.0101 (27-424)CM010716RZC52308 (residues 27-424)A0A4Y7IXT7 (residues 27-424) 
Pap s 1.0101 (425-846)CM010716RZC52308 (residues 425-846)A0A4Y7IXT7 (residues 425-846)