ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Pap s 3
Allergen source: Major taxonomic group: Plantae basal Mesangiosperms
Order: Ranunculales
Species: Papaver somniferum (Opium poppy)
NCBI Taxomony ID: 3469
Biochemical name:Late embryogenesis abundant protein 5 (LEA-5); small hydrophilic seed protein
MW(SDS-PAGE):10 kDa
Allergenicity:Of 36 tested poppy seed-sensitized patients (SPT, sIgE), 10 had allergic symptoms after oral food challenge. Of those, 8 allergic (80%) and 17 tolerant (65%) had IgE to natural Pap s 3 as shown by ELISA. As only the natural allergen was tested, which is a mixture of Pap s 3.0101 and Pap s 3.0201 (as shown by tandem MS), the contributions of the individual isoallergens to IgE binding was not determined.
Route of allergen exposure:Food
Date Created:2023-08-29
Last Updated:2023-08-29 18:32:50
Submitter Info:
Name:Aleksandra Podzhilkova, Merima Bublin
Institution:Department of Pathophysiology and Allergy Research, Medical University of Vienna
City:Vienna, Austria
Email:aleksandra.podzhilkova@muv.ac.at, merima.bublin@muv.ac.at
Submission Date:2023-05-11

Comments

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Pap s 3.0101CM010725RZC84488A0A4Y7LJ34 
Pap s 3.0201CM010725RZC84487A0A4Y7LHN0