Allergen Details
| Allergen name: | Der p 22 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Sarcoptiformes Species: Dermatophagoides pteronyssinus (European house dust mite) NCBI Taxomony ID: 6956 |
| Biochemical name: | NPC2 family; MD-2-related lipid recognition (ML) domain containing protein |
| Molecular mass: | 15 kDa |
| Allergenicity: | Of 149 sera from mite-allergic patients (reported symptoms + positive SPT to Der p extract), 80 (54%) had IgE to rDer p 22.0101 produced in E. coli, as determined by immuno-dot-blot. Signals were quatified using a human IgE standard, and 0.35 kU/L were used as a threshold for positive signals. Control sera from 27 non-allergic donors were negative. |
| Allergenicity reference: | PubMed:41036298 |
| Route of allergen exposure: | Airway |
| Created: | 2025-08-26 17:18:19 |
| Last Updated: | 2025-10-02 16:46:02 |
| Submitter Info: | |
| Name: | Kavita Reginald |
| Institution: | Sunway University, Faculty of Medical and Life Sciences |
| City: | Bandar Sunway, Selangor, Malaysia |
| Email: | |
| Submission Date: | 2025-05-23 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Der p 22.0101 | MF346044 | ATI08937 | A0A291KZA0 |