Allergen Details
| Allergen name: | Per a 23 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Blattodea Species: Periplaneta americana (American cockroach) NCBI Taxomony ID: 6978 |
| Biochemical name: | Glutathione S-transferase (GST) class sigma (related to Bla g 5) |
| Molecular mass: | 24 kDa |
| Allergenicity: | Sera from 68 cockroach-allergic patients (symptoms + SPT to P. americana extract) were tested by ELISA. Of those, 24 (35%) contained IgE to rPer a 23. Sera from five non-atopic donors did not bind to the allergen. |
| Route of allergen exposure: | Airway |
| Created: | 2026-02-16 14:12:30 |
| Last Updated: | 2026-02-16 15:57:12 |
| Submitter Info: | |
| Name: | Geoffrey Mueller; Josefina Zakzuk |
| Institution: | National Institute of Environmental Health Sciences; University of Cartagena |
| City: | Durham, NC, USA; Cartagena, Colombia |
| Email: | mueller3@niehs.nih.gov; jzakzuks@unicartagena.edu.co |
| Submission Date: | 2025-12-12 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Per a 23.0101 | KY661341 | AVA17428 | A0A2P0XJ18 |