Allergen Details
| Allergen name: | Tri a 46 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Liliopsida (monocots) Order: Poales Species: Triticum aestivum (Wheat) NCBI Taxomony ID: 4565 |
| Biochemical name: | rRNA N-glycosylase, ribosome-inactivating protein |
| Molecular mass: | 29 kDa |
| Allergenicity: | Sera from 65 wheat-allergic patients (symptoms + sIgE by ImmuoCAP) were tested. Of those, 6 sera (9%) had IgE to a 29 kDa protein in the water-soluble fraction as shown by immunoblot. All 6 sera bound to nTri a 46 in immunoblot as well as to nTri a 46 and rTri a 46 (expressed in E. coli) by ELISA. The natural and recombinant allergen showed comparable inhibitory capacities in an inhibition ELISA with immobilized nTri a 46. |
| Route of allergen exposure: | Food |
| Created: | 2026-09-03 16:49:47 |
| Last Updated: | 2026-09-03 16:50:21 |
| Submitter Info: | |
| Name: | Zhenxing Li; Yifei Wang |
| Institution: | Ocean University of China |
| City: | Qingdao, Shandong, China |
| Email: | lizhenxing@ouc.edu.cn; wangyifei123@stu.ouc.edu.cn |
| Submission Date: | 2026-04-22 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Tri a 46.0101 | PZ576291 | A0A3B6LV31 |