WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Blo t 2
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Blomia tropicalis (Storage mite)
NCBI Taxomony ID: 40697
Biochemical name:NPC2 family; MD-2-related lipid recognition (ML) domain containing protein
MW(SDS-PAGE):14.5 kDa
Allergenicity:15/243 by ELISA with recombinant
Allergenicity reference:PubMed:21332797
Route of allergen exposure:Airway
Date Created:05-11-2006
Last Updated:2023-11-09 13:25:00
Submitter Info:
Name:Fook Tim Chew
Institution:National University of Singapore
Submission Date:2006-12-06


Posted: 26 Oct 2014

There is little published evidence of allergy or IgE binding to the sequences previously recognized as Blo t 2. The submitters did not provide information for allergy to these proteins. However the 2011 publication by Kidon et al., indicates there were a number of subjects with IgE binding by direct ELISA with IgE to a slightly different sequence than any of the listed isoforms Blo t 2. That sequence is between 88% and 95% identical to the three indicated isoforms in IUIS. The reference is PMID 21332797. 26 Oct 2014 REG

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Blo t 2.0101AY288141AAQ73483Q1M2P1 
Blo t 2.0102AY288140AAQ73482Q1M2P2 
Blo t 2.0103AY288139AAQ73481Q1M2P3 
Blo t 2.0104DQ677253A6XEN8  
Blo t 2.0105ABG76186.1 ABG76186 A6XEN9