WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Cry j 1
Allergen source: Major taxonomic group: Plantae Pinopsida
Order: Cupressales
Species: Cryptomeria japonica (Sugi, Japanese cedar)
NCBI Taxomony ID: 3369
Biochemical name:Pectate lyase
MW(SDS-PAGE):41-45 kDa (45-50 kDa non-red)
Allergenicity:>90% of 145 sera from CJ pollinosis patients reacted with purified Cry j 1 in ELISA. Dose-dependent histamine release in 2 patients tested. - 12 out of 14 sera from patients with Japanese cedar pollinosis reacted with Cry j 1 in IgE ELISA: medline 90342988. - Purified allergen gives positive skin responses in intradermal skin test: medline 83109936.
Allergenicity reference:PubMed:8564723
Route of allergen exposure:Airway
Date Created:27-03-2003
Last Updated:2019-08-03 00:43:49
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Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cry j 1.0101D26544BAA05542P18632 
Cry j 1.0102D26545BAA05543P18632 
Cry j 1.0103D34639BAA07020P18632 
Cry j 1.0103AB081309BAB86286Q8RUR1 
Cry j 1.0103AB081310BAB86287Q8RUR1