Allergen Details
Allergen name: | Cte f 1 |
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Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Siphonaptera Species: Ctenocephalides felis (Cat flea) NCBI Taxomony ID: 7515 |
Biochemical name: | FS-1 |
MW(SDS-PAGE): | 18 kDa |
Allergenicity: | After 2 weeks of exposure to chambered fleas, all 30 experimentally sensitized dogs showed serum IgE binding to rCte f 1 in ELISA. Of 10 clinical flea-allergic dogs, 8 (80%) showed IgE binding to rCte f1 in ELISA. IgE binding to flea serum antigens could be inhibited by rCte f 1 > 80%. - All 6 sensitized dogs tested had positive intradermal skin test in response to recombinant Cte f 1. Frank,G.R. et al. Adv. Vet. Dermatol. 3, 201-212 (1998) |
Allergenicity reference: | PubMed:11074254 PubMed:8334536 |
Route of allergen exposure: | Injection |
Created: | 2003-06-17 12:00:00 |
Last Updated: | 2023-11-02 18:23:04 |
Submitter Info: | |
Name: | McDermott MJ et al. 2000 |
Institution: | Heska Corp. |
City: | Fort Collins, CO |
Email: | mcdermm@heska.com |
Submission Date: | 0000-00-00 |
Comments
Table of Isoallergens
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Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
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Cte f 1.0101 | U63555 | AAC69105 | Q94424 |