Allergen Details:
| Allergen name: | Fel d 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Chordata Order: Carnivora Species: Felis domesticus (F. catus) (Domestic cat) |
| Obsolete name: | cat-1 |
| Biochemical name: | Uteroglobin (chain 1) |
| MW(SDS-PAGE): | 38 kDa |
| Allergenicity: | >90% decrease in skin-test reactivity in cat-allergic patients was found after absorption of Fel d 1 from catdander extract. In RAST, a 76% reduction of IgE binding was found after depletion of Fel d 1 (medline 89054671). - recombinant chain 1 and chain 2: IgE binding in ELISA (medline 93254448) - IgE binding to nFel d 1 and rFel d 1 (medline 22304954) |
| Allergenicity reference: | PubMed:824067 |
| Route of allergen exposure: | Airway |
| Date Created: | 05-02-2003 |
| Last Updated: | 2019-08-17 02:21:38 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Fel d 1.0101 | M74952 (chain 1) M77341 (chain 2) | AAC37318 (chain 1) AAC41616 (chain 2) | P30438 (chain 1) P30440 (chain 2) | 1PUO |
| Fel d 1.A.0101 | AAC37318 | |||
| Fel d 1.B.0101 | AAC41616 |